There is no single “best” NAD+ provider — but there is a best provider for your situation, and four criteria that separate a trustworthy program from an expensive subscription: published all-in pricing, licensed-clinician oversight, cancel-anytime terms, and format options. Eight major telehealth providers sold at-home NAD+ as of mid-2026, clustered between $150 and $280 per month. This guide ranks them on those criteria, with every price capture-dated.
Transparency note: this comparison is published by Trellis Vitality. Our own program is included and clearly marked; we rank on stated criteria, not preference, and every competitor figure carries its source and capture date.
How we ranked
Four criteria, equally weighted: pricing transparency (is the all-in monthly cost published before checkout?), clinical oversight (does a licensed clinician review your intake before prescribing, with a path to ask questions after?), commitment terms (membership fees, contract tiers, cancellation), and format range (injection, patch, nasal spray for the needle-averse). We did not rank on marketing claims, and this category’s evidence base is the same molecule everywhere — the program around it is what differs.
Prices below are all-in where a membership is required, because that is the number you actually pay.
The rankings
1. Best all-around terms: Trellis Vitality — treatment plans from $129/mo
No membership fee, no contract, cancel anytime, licensed-clinician review before any prescription, HSA/FSA-eligible with prescription, and complete plan pricing published on the program page — treatment plans starting at $129 per month. We’re marking our own entry — judge it by the same table as everyone else.
2. Lowest all-in price: Strut Health — $150/mo
Physician-supervised at-home program at the bottom of the band, with no membership sitting on top of it. Fewer format options, and no quarterly lever.
3. Widest format range: AgelessRx — injection $235 · patch $160 · nasal $125 · cream $95
The only provider with four delivery formats, which matters if needles are the obstacle. No membership. Injection pricing sits above the category median.
4. Lab-led: Hone Health — $165/mo + $25/mo membership
Clinical, lab-forward model — but the membership fee takes the real price to ~$190/mo, and it’s easy to miss when comparing headline numbers.
5. Lowest medication price, membership required: Eden — from $119 medication + $99/mo membership
Eden advertises the cheapest medication figure in the category, but an active membership is required: $39 the first month, then $99/mo. That puts the ongoing all-in cost near $218/mo — above providers whose headline number looks higher. Worth comparing the supplied monthly dose too; a lower medication price can reflect a lower dose.
6. Quarterly value: Coby Health — $239/mo or $199/mo quarterly
Transparent pricing and a free consult; the quarterly discount brings it to $199/mo effective, still above the category’s lower band.
7. Contract-tiered: Brightmeds — $155–$246/mo
Doctor access is real, but pricing tiers by contract commitment — the lowest number requires the longest lock-in. Read exit terms first.
8. Premium app experience: IvyRx — $279/mo per 1,000 mg
App-supported and polished, priced at the top of the band. Lower-dose plans start around $199/mo; there is no quarterly lever at capture.
Comparison table (re-verified 2026-07-23)
| Provider | Monthly | All-in monthly | Membership | Contract | Formats | Clinician review |
|---|---|---|---|---|---|---|
| Trellis Vitality | Plans from $129/mo (program page) | Same — no additions | None | None — cancel anytime | Injection (more planned) | Yes, before every Rx |
| Strut Health | $150 | $150 | None | None | Injection | Physician-supervised |
| AgelessRx | $235 | $235 | None | None | Inj / patch / nasal / cream | Intake review |
| Hone Health | $165 | ~$190 | $25/mo | None | Injection | Lab-led |
| Eden | Medication from $119 | ~$218 ongoing | $99/mo (first month $39) | None | Injection | Intake review |
| Coby Health | $239 | $199/mo quarterly | None | None | Injection | Free consult |
| Brightmeds | $155–246 | $155–246 | None | Tiered | Injection | Doctor access |
| IvyRx | $279 per 1,000 mg | $279 (from $199 lower dose) | None | None | Injection | App-supported |
Brightmeds pricing carries its earlier 2026-06-10 capture; all other rows re-verified 2026-07-23.
How to choose (60-second version)
Needle-averse → start with a patch or nasal format (AgelessRx today; see our format comparison for how routes differ). Budget-first → Strut at $150 all-in, checking dose supplied. Want labs attached → Hone, counting the membership. Want no-contract flexibility with clinician review and published plan pricing from $129/mo → Trellis. For the line-by-line cost math including HSA/FSA, see our full price breakdown →. Whatever you choose, the four-signal trust check in the FAQ above applies everywhere.
NAD+ is prescribed and compounded by state-licensed, FDA-regulated compounding pharmacies. Compounded medications are not FDA-approved as finished products, and nothing here is a promise of results. Use is decided within a licensed clinical relationship.
Sources
- Provider pricing pages, re-verified 2026-07-23 (quarterly re-verification scheduled): eden.health; honehealth.com; get.agelessrx.com; cobyhealth.com; struthealth.com; ivyrx.com. Brightmeds via the vaccinealliance.org comparison, 2026-06-10 capture.
- Trellis Vitality published pricing (trellisvitality.com/products/nad), current as of 2026-07-23.