“What sold me was the muscle part. My last attempt dropped weight and strength both — here the protocol was built to hold the strength.”
Lose the fat.
Keep your muscle.
Hold your energy.
Rapid weight loss can cost you lean muscle — and your energy along with it. The Trellis program is designed to protect both: clinician-guided protocols, body-composition tracking that separates visceral fat from lean mass, and ongoing labs tailored to your goals.
Two Compounded GLP Treatments — All Dosages Available
- Semaglutide GLP-1 receptor agonist
- Mimics a natural gut hormone to lower blood sugar and suppress appetite.
- Tirzepatide GLP-1 & GIP receptor agonists
- Mimics two natural gut hormones to suppress appetite, slow digestion, and lower blood sugar levels.
Built around your
body composition.

Keep your muscle & your strength
In clinical studies of GLP-1 weight loss, roughly a third or more of the weight lost can be lean mass — not fat. The program pairs clinician guidance with options — from +glycine formulations to complementary protocols like tesamorelin — designed to help you achieve your body-composition goals and build strength while the excess fat comes off.

Lose the fat that matters most
Not all fat is equal. Visceral fat — the deep fat around your organs — is the kind most closely tied to metabolic health. The program measures it, alongside lean mass, so the weight you lose is the kind that improves your baseline, not just the number on the scale.

Steady energy throughout your treatment
Appetite suppression can drop your intake — and your energy — faster than your body adapts. Protein targets, hydration and electrolyte guidance, and labs that catch B12, vitamin D, and iron gaps are built into the protocol, so fatigue gets addressed, not endured.

Personalized online clinical care
A licensed clinician reviews your intake and any lab data to determine if medication is appropriate and which formulation fits your needs. Your clinical team stays with you — guiding and monitoring the program as your body adjusts, so your protocol keeps pace with your progress.

Program flexibility
Already on a compounded program? Move your care to our guided program and upload your recent labs. Our clinical support team will review your data and recommend protocol adjustments — free.
Members, in their own words.
Select reviews on the program experience and what changed in their body composition — not the scale alone.
“The clinician actually reviewed my labs and said what fit. It felt like care, not a checkout.”
“I moved my care over from another compounded program. Same continuity, but now with body-composition tracking and real oversight.”
“Body-composition numbers, not just the scale. Watching fat go down while lean held is the whole reason I stayed.”
Compare the model
A supervised program, not a mail-order molecule.
| Trellis ProgramSupervised | Commodity GLP-1Ship-a-vial | Going It AloneUnsupervised | |
|---|---|---|---|
| Clinician oversight | Ongoing review and individualized dosing | Minimal — checkout-style intake | None |
| Muscle-preservation protocol | Resistance-training + protein protocol included | Not offered | On your own |
| Body-composition tracking | Labs + monitoring, fat vs. lean over time | Scale only, if that | None |
| Ongoing labs | Baseline + 90-day re-test | Rarely | None |
Compounding & fulfillment
Our United States Compounding Pharmacy is World Class
Our U.S. state-licensed, USP-compliant sterile lab compounds your physician-supervised, personalized medications. After completing four independent quality and accuracy tests, our precision operations team cold packs and ships your order via UPS. From order intake to shipment in 24–48 hours.
Every batch quality tested for
THE EDUCATION
Why lean mass matters.
GLP-1 medications (semaglutide) and dual GIP/GLP-1 medications (tirzepatide) act on receptors that affect appetite regulation and gastric emptying — that's the neutral mechanism, not a promise. Here's the part most weight-loss plans skip: rapid weight loss can cost lean muscle, and losing muscle is the wrong kind of loss. That concern is real and evidence-based, and it's why the Trellis program is built around protecting it — a resistance-training and protein protocol, clinician oversight, and body-composition monitoring that tracks fat versus lean mass. A clinician determines whether medication is appropriate for you; where it is, dosing is individualized. Compounded medication is not FDA-approved as a finished product.
Program questions.
Straight answers on the program, the medications, safety, and sourcing — no hype.
What is the Trellis weight & metabolic program?
It’s a clinician-supervised program built around your body composition — a free clinical assessment, a Vitality Lab Kit for a metabolic and body-composition baseline, a resistance-training and protein protocol, ongoing monitoring, and a 90-day re-test. Where a clinician determines it’s appropriate, medication is one component of the plan. The program is the product; the medication is a step within it.
How does the program help protect muscle?
Rapid weight loss can cost lean muscle. The program is designed to help protect it — through a resistance-training and protein protocol, clinician oversight, and body-composition monitoring that tracks fat versus lean mass over time. That’s a design of the program, not a claim about any medication.
Is the medication FDA-approved?
No. Where a clinician prescribes it, the medication is compounded and patient-specific — prepared per prescription by a state-licensed compounding pharmacy (Vials Rx). Compounded medications are not FDA-approved as finished products, and we don’t describe them as equivalent to any branded product. We say this plainly because it matters.
What’s the difference between semaglutide and tirzepatide?
They act on different receptors: semaglutide is a GLP-1 receptor agonist, and tirzepatide is a dual GIP/GLP-1 receptor agonist. Both affect appetite regulation and gastric emptying. Which one — if either — fits you is a clinical decision your clinician makes with you; we don’t rank one as “best” or “strongest.”
What are the +glycine and microdose formulations?
They’re neutral, clinician-determined formulation and dosing options — nothing more. A clinician may titrate dose or select a formulation based on your clinical picture. We don’t present any formulation or dose as a special benefit or a longevity feature; it’s simply part of individualizing care.
Will I definitely get a prescription?
No. A clinician determines whether the program and any medication are appropriate for you. There are no guaranteed prescriptions and no skipping the clinical review.
Is it safe? What are the side effects?
GLP-1 and GIP/GLP-1 medications most commonly cause gastrointestinal effects (nausea, and other GI symptoms), usually managed by titration. There are serious considerations and contraindications — including a personal or family history of medullary thyroid carcinoma or MEN 2, a history of pancreatitis, and pregnancy — which is exactly why a clinician reviews your full health context before anything is prescribed.
Can I use my HSA / FSA? Is it covered by insurance?
The program is HSA/FSA-eligible for most US plans, and we provide an itemized superbill on request. It generally isn’t billed to insurance — you pay for the program monthly, and many members offset the cost with HSA/FSA dollars.
I’m already on a compounded program — can I switch?
Yes. Many members move their care to a supervised model with labs and body-composition tracking. It’s framed as continuity of care — bringing your program under clinician oversight — not a pitch about a cheaper molecule.
How is the medication compounded and where does it come from?
Where prescribed, it’s compounded per prescription by Vials Rx, a US state-licensed, cGMP-compliant pharmacy, and quality-tested by batch for potency, sterility (USP <797>), pH, and endotoxicity (USP <85>) before it ships.
Do I need lab work?
Yes — a baseline via the Vitality Lab Kit and ongoing monitoring are part of the program. They’re how progress is measured against your body composition rather than just the scale.
What states do you serve?
The program is available through affiliated clinicians and pharmacy partners in accordance with state licensure and regulation. Availability varies by state, and this program is not offered in every state — including certain states where we currently suppress it (Connecticut, Ohio, and South Carolina at minimum). Your eligibility is confirmed during the assessment.
Can I combine this with other Trellis protocols?
Often, yes — your clinician reviews your full picture. Some members add energy or metabolic support (Lipo-MIC + B12) or a cellular-energy protocol (NAD⁺) alongside the program. Any combination is a clinician decision based on your labs and goals.
What happens after I lose the weight?
The program includes a maintenance path, and some members later move to separate protocols for body composition or the growth-hormone axis. Those are distinct protocols with their own clinical review — not a claim about what the GLP-1 program itself does over the long run.